Product

Introducing BlueCheck™

BlueCheck™ Caries detection and monitoring

Incisive Technologies’ first product, is a device which aids dental professionals in the visualisation of carious lesions. Using the natural chemistry of proteins the BlueCheck molecule has an affinity for and targets porous surface and sub-surface lesions (hydroxyapatite).

Dental caries (tooth decay) is one of the most prevalent chronic diseases worldwide, which is progressive in development, affecting individuals throughout their lifetime.

BlueCheck™ specifically and reversibly binds to active caries lesions and provides a visible blue color to the tooth surface at sites of demineralization. Healthy enamel and arrested lesions do not turn blue.

BlueCheck™ is intended to provide objective evidence on caries lesion status to aid the clinician during routine examination as part of diagnosis, treatment planning and for ongoing monitoring.

BlueCheck is US FDA Cleared and available for use by dental professionals across the US.

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Publications

  • Mangum J, et al. Surface Integrity Governs the Proteome of Hypomineralized Enamel. J Dent Res 89 (10):1160-1065, 2010.

  • Jablonski-Momeni A, et al. Ability of BlueCheck liquid stain as a novel technology to detect initial enamel demineralization. Car Res 2022; 56:555-565.

  • Lippert F, et al. Detection of Artificial Enamel Caries-like Lesions with a Blue Hydroxyapatite-Binding Porosity Probe. J of Dent, 135, 2023 104601.

  • White J, et al. Assessment of two methods for detecting carious dentin: an in vitro study. BMC Oral Health 25, 258 (2025). 

  • White J, et al. Assessment of two novel methods for detecting non-cavitated, smooth surface enamel lesions: an in vitro study. BMC Oral Health 25, 843 (2025). 

  • Poster: Mascarenhas R, et al. Investigation of a novel diagnostic for early detection of white spot lesions. ASO, March 2022.

  • Poster: Lippert F, et al. Investigating the ability of a blue dye to selectively stain early enamel caries lesions. ORCA, July 2022.

  • Poster: Jablonski-Momeni A, et al. In-vitro performance of BlueCheck liquid as a novel technology for detection of initial enamel demineralization. ORCA, July 2022.

  • Poster: Jablonski-Momeni A, et al. In-vitro performance of BlueCheck liquid for detection of initial lesions on occlusal surfaces. ORCA, July 2023.

  • Poster: Mangum J, et al. BlueCheck: A hydroxyapatite-binding porosity probe for sensitive detection of carious lesions. IADR, March 2024.

  • Poster: Dai R, et al. Detecting Initial Enamel Caries in Orthodontic Patients with BlueCheck. A Pilot Study. ASO, March 2024. 

  • Poster: Jablonski-Momeni A, et al. A new early caries detection aid (BlueCheck) does not inhibit remineralisation of artificial enamel caries. ORCA, June 2024. 

  • Poster: Kukreti P, et al. Usability Evaluation of a Novel Tooth Decay Indicator. AADOCR, March 2025.

  • Poster: Hegarty K et al. Comparative evaluation of Techniques for detecting early occlusal carious lesions. AAC, September 2025.